Polio eradication has been a significant global health challenge, particularly in countries like Nigeria and India, which were once epicenters of the disease. This systematic review examines the key challenges faced and the strategies implemented in these two nations that ultimately led to the successful eradication of polio. In both countries, hurdles such as vaccine hesitancy, logistical difficulties, political instability, and socio-cultural barriers impeded progress. However, through coordinated efforts involving government agencies, international organizations, and local communities, significant strides were made. Vaccination campaigns, public health awareness, surveillance systems, and infrastructure improvements played critical roles in overcoming these obstacles. By comparing the experiences of Nigeria and India, this review highlights the lessons learned and provides insights for future global health initiatives aimed at eradicating other diseases. The findings emphasize the importance of community engagement, political will, and sustained efforts in achieving global public health goals.

Polio eradication, vaccination campaigns, global health

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