According to the World Health Organization (2016), 1.9 billion people worldwide (every fourth) are overweight or obese. Insulin resistance is a complex multifactorial process based on the interaction of genetic, hormonal and external factors. Insulin resistance is called one of the main causes of obesity and a trigger for type 2 diabetes mellitus, hypertension, coronary heart disease, liver and kidney disease, infertility in women, erectile dysfunction in men and even Alzheimer's disease. Modern lifestyle characterized by a sedentary lifestyle, high-calorie diet and stress increases the risk of developing insulin resistance. It is important to study how these factors affect children in order to develop effective preventive measures.

Insulin resistance, pathogenesis, etiological factors

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