Articles | Open Access | https://doi.org/10.55640/ijmm-03-10-03

POSSIBILITIES OF PREDICTING THE OUTCOME OF THE COURSE OF ACUTE PURULENT-DESTRUCTIVE LUNG DISEASES IN PATIENTS WHO HAVE HAD SARS-COV-2

Bobokulova Shokhista Abdualimovna , Tashkent Medical Academy, Department of General and Pediatric Surgery-1, PhD, Senior Lecturer, Tashkent, Uzbekistan

Abstract

Since the discovery of COVID-19, purulent-destructive lung diseases have been increasingly described and diagnosed around the world in patients who have fallen ill with or have had covid pneumonia. Treatment of purulent diseases of the lungs and pleura invariably remains an urgent problem. This pathology, painful for the patient, time-consuming for the doctor and expensive for the medical institution, combines intoxication due to a purulent-destructive process and impaired respiratory function.  The occurrence of infectious destruction of the lungs and pleura is facilitated by immunodeficiency and immunosuppression, which are characteristic of patients suffering from haematological diseases, increased tendency to thrombosis, diabetes mellitus, alcoholism, drug addiction, HIV infection, who have undergone extensive surgical interventions, organ and tissue transplantation. The peculiarity of the course of COVID lung infection is the consolidation of an inflammatory focus in the lungs, which can lead to the formation of abscesses and gangrene of the lungs, and sepsis, which is associated with high mortality in the long term after COVID disease. At the moment, the exact mechanism of development is not known, but it may be associated with diffuse alveolar damage, intraalveolar bleeding, stenosis or occlusion of alveolar arterioles, their thrombosis and, as a consequence of the above, necrosis of the cell parenchyma. Another factor in the occurrence of acute purulent-destructive lung diseases is pneumofibrosis, which is a frequent occurrence after covid pneumonia. A lung abscess is a necrotic lesion that forms a cavity filled with pus in the lung parenchyma with a characteristic level of fluid in the air on a chest X-ray. Most often, the cause of severe covid pneumonia is not only a virus but bacterial and fungal superinfection, including those associated with mechanical ventilation.

Keywords

Acute purulent-destructive lung diseases, SARS-COV-2, prediction of disease outcome

References

Lung abscess as a complication of COVID-19-pneumonia: a clinical case / T. I. Kalenchits, S. L. Kabak, S. V. Primak, N. M. Shirinaliev // Tuberculosis and lung diseases. – 2021. – T. 99, No 12. – P. 7-13. Russian

Lung abscess based on the materials of the pulmonological department of the OKB, Barnaul / E. B. Klister, G. V. Trubnikov, S. I. Oleynik et al. // 13th National Congress on Respiratory Diseases: Collection of Abstracts, St. Petersburg, November 10–14, 2003. – St. Petersburg: Universum Publishing, 2003. – P. 145. Russian

Assessment of manifestations of morbidity of the population with acute lung abscesses in a large industrial centre / I. A. Balandina, R. V. Khokhryakov, N. M. Koza et al. // Perm Medical Journal. – 2009. – T. 26, No 3. – P. 136-138. Russian

Certificate of State Registration of the Database No 2020622809 Russian Federation. Database of patients operated on for gangrene and gangrenous abscesses of the lung: No 2020622744: application. 21.12.2020: publ. 25.12.2020 / O. E. Karyakina; applicant: Federal State Autonomous Educational Institution of Higher Education "Northern (Arctic) Federal University named after M.V. Lomonosov". Russian

Sergevnin V.I., Khokhryakov R.V., Gusmanova P.S. Lung abscess: groups and risk factors of morbidity and mortality, prognostically unfavourable clinical symptoms. - 2011. - №2. - C. 12-17. Russian

Shubin I. V., Prisyazhnyuk N. V. Chronic lung abscess (clinical observation) // Medical Bulletin of the Ministry of Internal Affairs. – 2009. – № 4(41). – P. 37-39.

Impact of dexamethasone on the incidence of ventilator-associated pneumonia and bloodstream infections in COVID-19 patients requiring invasive mechanical ventilation: A multicenter retrospective study. / I. Gragueb-Chatti, A. Lopez, D. Hamidi, et al. // Ann Intensive Care. 2021; P. 11:87.

Lung abscess in critically ill coronavirus disease 2019 patients with ventilator-associated pneumonia: a French monocenter retrospective study / V. Beaucoté, G. Plantefève, J.A.Tirolien, P.Desaint // Crit. Care Explor. - 2021. - Vol. 3, № 7. - Р. e0482.

Pulmonary cavitation following pulmonary infarction. / L.S Libby, T.E. King, F.M. LaForce et al. // Medicine (Baltimore).-1985-64:P.342–348.

Pulmonary embolism or thrombosis in ARDS COVID-19 patients: A French monocenter retrospective study. / D. Contou, O.Pajot, R.Cally, et al. // PLoS One. 2020; 15:e0238413.

Pulmonary vascular endothelialitis, thrombosis, and angiogenesis in Covid-19. / M. Ackermann, S.E. Verleden, M. Kuehnel, et al. // N. Engl. J. Med. 2020; 383: P. 120–128.

Relationship between SARS-CoV-2 infection and the incidence of ventilator-associated lower respiratory tract infections: A European multicenter cohort study. / A. Rouze, I. Martin-Loeches, P. Povoa, et al. // Intensive Care Med. 2021; 47:P. 188–198.

Ripa M., Galli L., Poli A. Secondary infections in patients hospitalised with COVID-19: incidence and predictive factors. // Clin. Microbiol. Infect. 2021;27(3):451–457.

Risks of ventilator-associated pneumonia and invasive pulmonary aspergillosis in patients with viral acute respiratory distress syndrome related or not to coronavirus 19 disease. / K. Razazi, R. Arrestier, A.F. Haudebourg, et al. // Crit Care. 2020; P. 24:699.

Treatment of acute lung abscesses considering their non-respiratory function in patients with diabetes / A. O. Okhunov, R. I. Israilov, S. A. Khamdamov et al. // Indian Journal of Forensic Medicine and Toxicology. – 2020. – Vol. 14, No. 4. – P. 7465-7469.

Umamoto K., Horiba M. Lung abscess as a secondary infection of COVID-19: A case report and literature review. // J Infect Chemother.-2023 Feb 13:S1341-321X(23)00041-7.

Ventilator-associated pneumonia in patients with SARS-CoV-2-associated acute respiratory distress syndrome requiring ECMO: A retrospective cohort study. / C.E. Luyt, T. Sahnoun, M. Gautier, et al. // Ann Intensive Care.-2020; № 10:P. 158.

Wicky P.H., Niedermann M.S., Timsit J.F. Ventilator-associated pneumonia in the era of COVID-19 pandemic: How common and what is the impact? // Crit. Care. 2021; № 25:P.153.

Yazbeck M. F., Dahdel M., Kalra A. Lung abscess: update on microbiology and management. Am. J. Ther. 2014;21(3):217-221.

Zamani N., Aloosh O., Ahsant S. Lung abscess as a complication of COVID-19 infection, a case report. // Clin Case Rep.-2021 Jan 25;9(3):1130-1134.

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POSSIBILITIES OF PREDICTING THE OUTCOME OF THE COURSE OF ACUTE PURULENT-DESTRUCTIVE LUNG DISEASES IN PATIENTS WHO HAVE HAD SARS-COV-2. (2024). International Journal of Modern Medicine, 3(10), 14-22. https://doi.org/10.55640/ijmm-03-10-03