It is known that modern surgery of adhesions should combine minimally invasive technologies, the use of agents that create a protective layer on the damaged areas of the peritoneum, the use of drug forms that activate the processes of mesothelial repair. This is already a mandatory attribute of operations and the will of today's requirements. In this report, we tried to reflect the technical issues of the use of the anti-adhesion membrane as a prophylactic agent in patients in abdominal surgery. We used this innovative drug in 18 patients with adhesive intestinal obstruction and with the possibility of its use in traditional and laparoscopic surgery.

Abdominal surgery, adhesive intestinal obstruction, anti-adhesion membrane agents

Crha I., Ventruba P., Petrenko M., Visnova H. Present possibilities of prevention of adhesions and their immunologic aspects // Ceska Gynekol. - 2019. - V 6 4 . N 4 . - P . 230-234.

Cubukcu A., Alponat A., Gonullu N.N. MitomycinC-prevents reformation of intra-abdominal adhesions after adhesiolysis // Surgery. — 2002. -Vol. 131, №1. - P . 81-84.

Duron J J., Ellian N, Olivier O. Post-operative peritoneal adhesions and foreign bodies // Europ J. surg. Suppl. — 2017. — № 579. — P. 15-16.

Enrico S., Pecchio A., Mineccia M., Mello-Teggia P. Postoperative intraabdominal adhesions: prevention and treatment // Minerva Chir. — 2016. - Vol. 5 1 , № 4 . - P . 223-226.

Frishman G.N., PelusoJJ., Kratka S.A. et al. Preoperative versus postoperative dextran 70 for preventing adhesion formation //J. Reprod Med. - 2021. - Vol. 36, № 10. - P. 707-710.

Gluckman T.J., Li-Cheng-Wu M., Pins M.R., Johnson S. Pathologic quiz case. Abdominal mass with adhesions // Arch. Path. Lab. Med. — 2000. - Vol. 124, № 6 . - P . 915-916.

Gomel V., Urman В., Gurgan T. Pathophysiology of adhesion formation and strategies for prevention //J. Reprod. Med. — 2016. — Vol. 41, № 1. P. 35-41.

Halverson A.L., Barrett W.L., Bhanot P. et al. Intraabdominal adhesion formation after preperitoneal dissection in the murine model // Surg. Endosc. - 2019.-Vol. 13, № 1 . - P . 14-16.

Holtz G. Prevention of postoperative adhesions //J. Reprod. Med. - 2000. - Vol. 24, № 4. P. 141-146.

Jacquet P., Sugarbaker P.H. Effects of postoperative intraperitoneal chemotherapy on peritoneal wound healing and adhesion formation / / Cancer Treat. Rep. - 2016. - Vol. 82, P. 327-335.

Kodama I., Loiacono L.A., Sigel B. et al. Ultrasonic detection of viscera slide as an indicator of abdominal wall adhesions 111. clin. Ultra-sound. - 2014. - Vol. 20, № 6 . - P . 375-380.

Kolecki R.V., Golub R.M., Sigel B. et al. Accuracy of viscera slide detection of abdominal wall adhesions by ultrasound / / Surg. Endosc. — 2014. - Vol. 8, № 8. - P. 871-874.

Koltai J.L., Gerhard A. Intraperitoneal application of fibrinogen gluing in the rat for adhesions prophylaxis / / Progr. Pediatr. Surg. — 2020. — Vol. 25. - P. 71-80.

Kuebelbeck K.L., Slone D.E., May KA. Effect of omentectomy on adhesion formation in horses / / Vet. Surg. — 2017. — Vol. 27, № 2. P. 132-137.

Lai H.S., Chen Y., Chang K.J., Chen W.J. Tissue plasminogen activator reduces intraperitoneal adhesion after intestinal resection in rats // J. Formos. Med. Assoc. - 2018. - V 97. N 5. - P. 323-327.

Luijendijk R.W., de Lange D.C., Wauters C.C. et*al. Foreign material in postoperative adhesions //J. Ann. Surg. — 2016. — Vol. 223, № 3. — P. 242-248.

Moreno A., AguayoJ.L., Zambudio G. et al. Influence of abdominal incision on the formation of postoperative peritoneal adhesions: an experimental study in rats / / Europ. J. surg. - 2016. - Vol. 162, № 3. - P. 181-185.

Muller S.A., Treutner K.H., Tietze L. et al. Influence of early drainage of intraperitoneal phospholipids on efficacy of adhesion prevention / / J. invest. Surg. - 2017. - Vol. 15, № 1. - p. 23-28.